منابع مشابه
Case Series of Hepatoblastoma
Background: In the past 20 years, a dramatic improvement in the prognosis of patients with hepatoblastoma (HB)has been achieved by combining surgery and chemotherapy in several national and international trials.Materials and Methods: Four children ( 3 girl and 1 boy) aged 34 days, 4 months, 13 months, and 1 year with meanage of 6.53 (±5.15) months were presented to our center from 2002 to 2009 ...
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Graves' disease is an autoimmune disorder, caused by thyroid-stimulating antibodies, which bind to and activate the thyrotropin receptor on thyroid cells, inducing the synthesis and release of thyroid hormones. It is a polygenic and multifactorial disease that develops as a result of complex interaction between genetic susceptibility and environmental and/or endogenous factors. Graves' disease ...
متن کاملEtiopathogenesis of otosclerosis.
Otosclerosis is a frequent cause of nonsyndromic hearing loss which affects exclusively the human temporal bone. Various etiopathogenetic hypotheses have been proposed. The major hypotheses considered are genetic factors, immunologic factors and viral infection. Since the familial incidence of otosclerosis is known a recent genetic analysis has given evidence of three otosclerosis genes (OTSC1-...
متن کاملEtiopathogenesis of Insulin Autoimmunity
Autoimmunity against pancreatic islet beta cells is strongly associated with proinsulin, insulin, or both. The insulin autoreactivity is particularly pronounced in children with young age at onset of type 1 diabetes. Possible mechanisms for (pro)insulin autoimmunity may involve beta-cell destruction resulting in proinsulin peptide presentation on HLA-DR-DQ Class II molecules in pancreatic drain...
متن کاملHepatoblastoma: when to screen?
Introduction Hepatoblastoma is a rare hepatic malignancy that is seen in Familial Adenomatous Polyposis (FAP). The occurrence is four hundred fold higher than the general population [1]. Hepatoblastoma is generally treatable with surgery; in addition it is highly responsive to chemotherapy. While the literature reports on this extracolonic manifestation of FAP, no screening recommendations exis...
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ژورنال
عنوان ژورنال: Journal of Carcinogenesis & Mutagenesis
سال: 2016
ISSN: 2157-2518
DOI: 10.4172/2157-2518.1000e120